Cruising Review

Effects of PEMF on Adults with MS

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Comprehensive review of Bemer and PEMF (Pulsed Electromagnetic Field). Explore scientific research, studies, and articles on the benefits and applications of Bemer and PEMF therapy for health and wellness.

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Brazilian Journal of Physical Therapy 26 (xxxx) 100449
Brazilian Journal of
Physical Therapy
Effects of pulsed electromagnetic field therapy on fatigue, walking performance, depression, and quality of life in adults with multiple sclerosis: a randomized placebo-controlled trial
Anabel Granja-Domíngueza, Anja Hochsprungb, Carlos Luque-Morenoc,d,*, Eleonora Magnic, Shahid Escudero-Uribeb, Beatriz Heredia-Camachoe, Guillermo Izquierdo-Ayusoa, Alberto Marcos Heredia-Rizoc,f
a Fundacion DINAC, Hospital Vithas Nisa, Sevilla, Spain
b Hospital Universitario Virgen Macarena, Andalusian Health Service, Sevilla, Spain
c Physical Therapy Department, Faculty of Nursing, Physical Therapy and Podiatry, University of Sevilla, Sevilla, Spain d Instituto de Biomedicina de Sevilla (IBIS), Sevilla, Spain
e Centro de Fisioterapia Fisin, Dos Hermanas, Sevilla, Spain
f UMSS Research Group, University of Sevilla, Sevilla, Spain
Received 9 September 2021; received in revised form 8 September 2022; accepted 3 October 2022 Available online 13 October 2022
Magnetic field therapy; Neurologic gait disorders;
Placebo effect; Quality of life; Relapsing-remitting multiple sclerosis
Background: Multiple sclerosis has a great disability burden. Management of the disease is com- plex, and patients often seek new conservative approaches.
Objective: To investigate the effect of low-frequency pulsed electromagnetic field (PEMF) ther- apy, compared to placebo, on the level of fatigue, walking performance, symptoms of depres- sion, and quality of life (QOL) in patients with relapsing-remitting multiple sclerosis (RRMS). Methods: Forty-four adults with RRMS and minimal to significant disability were randomly assigned to a 4-week protocol using a PEMF or a placebo whole-body mat. The PEMF group were initially treated with 15Hz frequency, gradually increased to 30Hz (intensity between 25-35mT). The primary outcome was fatigue, assessed with the Fatigue Severity Scale (FSS) and the Modi- fied Fatigue Impact Scale (MFIS). Secondary measures included walking function (GAITRite sys- tem and Timed 25-Foot Walk test), the Beck Depression Inventory-II, and the Multiple Sclerosis International Quality of Life Questionnaire. Data were collected at baseline, after intervention, and at 3-months post-intervention (follow-up).
Results: There were no differences between groups for changes in fatigue symptoms from base- line to end of intervention (mean and 95% confidence interval FSS: -0.6, 95%CI: -1.3, 0.1; MFIS:
* Corresponding author at: Departamento de Fisioterapia, Facultad de Enfermería, Fisioterapia y Podología, Universidad de Sevilla, c/ Avi- cena s/n, 41009, Sevilla, Spain.
E-mail: (C. Luque-Moreno).
1413-3555/© 2022 Associação Brasileira de Pesquisa e Pós-Graduação em Fisioterapia. Published by Elsevier España, S.L.U. All rights reserved.

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