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BIPHASIC DOSE RESPONSE IN LOW LEVEL LIGHT THERAPY AN UPDATE

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BIPHASIC DOSE RESPONSE IN LOW LEVEL LIGHT THERAPY AN UPDATE ( biphasic-dose-response-in-low-level-light-therapy-an-update )

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Y-Y. Huang and others neous patient population, as compared with a highly uniform population of experimental animals (inbred lab animals are genetically identical). ACKNOWLEDGMENTS This work was supported by NIH grant R01AI050875, Center for Integration of Medicine and Innovative Technology (DAMD17-02-2- 0006), CDMRP Program in TBI (W81XWH-09-1-0514) and Air Force Office of Scientific Research (FA9950-04-1-0079). REFERENCES al-Watban FA and Andres BL 2001. The effect of He-Ne laser (632.8 nm) and Solcoseryl in vitro. Lasers Med Sci 16(4): 267-275. Anders J, Romanczyk T, Moges H, Ilev I, Waynant R and Longo L 2007. Light Interaction With Human Central Nervous System Progenitor Cells. NAALT conference proceedings. 2007. Ball KA, Castello PR and Poyton RO 2011. Low intensity light stimulates nitrite-dependent nitric oxide synthesis but not oxygen consumption by cytochrome c oxidase: Implications for pho- totherapy. J Photochem Photobiol B 102(3): 182-191. Bjordal JM, Couppe C, Chow RT, Tuner J and Ljunggren EA 2003. A systematic review of low level laser therapy with location-specific doses for pain from chronic joint disorders. Aust J Physiother 49(2): 107-116. Bolton P, Young S and Dyson M 1990. Macrophage responsiveness to light therapy: a dose response study. Laser Ther 2: 101-106. Bolton P, Young S and Dyson M 1991. Macrophage responsiveness to light therapy with varying power and energy densities. Laser Therapy 3(3): 105-112. Borutaite V, Budriunaite A and Brown GC 2000. Reversal of nitric oxide-, peroxynitrite- and S- nitrosothiol-induced inhibition of mitochondrial respiration or complex I activity by light and thiols. Biochimica et biophysica acta 1459(2-3): 405-412. Brea-Calvo G, Siendones E, Sanchez-Alcazar JA, de Cabo R and Navas P 2009. Cell survival from chemotherapy depends on NF-kappaB transcriptional up-regulation of coenzyme Q biosynthe- sis. PLoS One 4(4): e5301. Brondon P, Stadler I and Lanzafame RJ 2005. A study of the effects of phototherapy dose interval on photobiomodulation of cell cultures. Lasers Surg Med 36(5): 409-413. Castano AP, Dai T, Yaroslavsky I, Cohen R, Apruzzese WA, Smotrich MH and Hamblin MR 2007. Low- level laser therapy for zymosan-induced arthritis in rats: Importance of illumination time. Lasers Surg Med 39(6): 543-550. Chandel NS, Trzyna WC, McClintock DS and Schumacker PT 2000. Role of oxidants in NF-kappa B activation and TNF-alpha gene transcription induced by hypoxia and endotoxin. J Immunol 165(2): 1013-1021. Chen AC-H, Arany PR, Huang Y-Y, Tomkinson EM, Saleem T, Yull FE, Blackwell TS and Hamblin MR 2009. Low level laser therapy activates NF-κB via generation of reactive oxygen species in mouse embryonic fibroblasts. Proc. SPIE 7165: pp. 71650B. Demidova-Rice TN, Salomatina EV, Yaroslavsky AN, Herman IM and Hamblin MR 2007. Low-level light stimulates excisional wound healing in mice. Lasers Surg Med 39(9): 706-715. Gal P, Mokry M, Vidinsky B, Kilik R, Depta F, Harakalova M, Longauer F, Mozes S and Sabo J 2009. Effect of equal daily doses achieved by different power densities of low-level laser therapy at 635 nm on open skin wound healing in normal and corticosteroid-treated rats. Laser Med Sci 24(4): 539-547. Ginsbach G 1979. Laser induced stimulation of wound healing in bad healing wounds. Proc Laser ‘79 Opto Elektronics Conf Munich. IPC Science and Technology Press Guildford UK: 5. Greco M, Guida G, Perlino E, Marra E and Quagliariello E 1989. Increase in RNA and protein syn- thesis by mitochondria irradiated with helium-neon laser. Biochem Biophys Res Commun 163(3): 1428-1434. Groeger G, Quiney C and Cotter TG 2009. Hydrogen peroxide as a cell-survival signaling molecule. Antioxid Redox Signal 11(11): 2655-2671. 616

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