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298 A. SCALBERT ET AL. but it also reduces the life-span of mice, when added to the diet on a long term basis.301 It can be anticipated that the most protective polyphenols and the most appropriate levels of intake will be determined in the near future, for both the general population and pop- ulations at risk of developing particular diseases. Before this goal is reached, caution is necessary before recommending to increase their consumption. This is particularly important for dietary supplements, as their promotion may result in increases of polyphenol intake, sometimes far-exceeding the common in- take levels associated to the diet. Once the most protective levels of polyphenol intake are been established, it will be possible to improve the quality of food through plant breeding or food pro- cessing, and to make sound dietary recommendations for an effective health benefit. REFERENCES [1] Scalbert, A. and Williamson, G. 2000. Dietary intake and bioavailability of polyphenols. J. 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Nutr., 69:87–94. high-performance liquid chromatography. Methods Enzymol., 233:324–PDF Image | Dietary Polyphenols and the Prevention of Diseases
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