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Treatment of dry Age-related Macular Degeneration with Photobiomodulation Graham Merry MBBS, LMCC1, Robert Devenyi MD, MBA, FRCSC, FACS, DABO2, Robert Dotson MD, FAAO3, Samuel N. Markowitz, MD, FRCSC4, Sophia V. Reyes, MD4, 1 Photospectra Health Sciences Inc. Toronto, Ontario, Canada, 2 Department of Ophthalmology and Vision Sciences, University Health Network, Toronto, Ontario, Canada, 3Private Practice, Oak Ridge, Tennessee, USA, 4Low Vision Service, Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada. Correspondence to: Dr. Graham Merry, Suite 101, 190 Cundles Road East Barrie, Ontario, L4M 4S5 Tel: (705) 728 0800 Fax: (416) 636 5408 Email: gmerry@photospectra.ca Word count: 3381 Presented at ARVO, Fort Lauderdale, May 7, 2012 ABSTRACT Objective: To evaluate if Photobiomodulation (PBM) can affect vision in patients with dry Age-Related Macular Degeneration (AMD). Methods: Prospective interventional case series. Near Infra Red (NIR) and yellow wavelengths of low powered light were applied to eyes with AMD in serial consecutive treatments. Included were patients with dry AMD, 50 years or older and with visual acuity between 20/20 - 20/200. Primary outcome measures selected were change in visual acuity, contrast sensitivity and fixation stability. Results: The treatment protocol was completed in 18 eyes (9 patients). Changes in visual acuity (p<0.0001) and contrast sensitivity (p<0.0001 at 3 cycles/degree and p<0.0032 at 1.5 cycles/degree) were positive and significant. There were no significant changes in fixation stability parameters.PDF Image | dry Age-related Macular Degeneration Photobiomodulation
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