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46 thorough understanding of the influence of such factors as age, as well as provide a larger data set for other statistical modelling in consideration of patient specific variables (eg. sex, which teeth where undergoing retraction, LED-device compliance and dose-effect relationships). In addition to a larger sample size, the assessment of changes in extraction space size at more frequent time points would facilitate a better understanding of any temporal changes in OTM as extraction spaces are closed and if LED phototherapy has time-dependent effects. This extension of the number of visits to the study protocol, although challenging from an ethical and clinical management standpoint, would give insights into if IR-LED phototherapy is beneficial during certain phases of OTM and therefore orthodontic treatment. 4.6 CONCLUSIONS The results of this study showed that extra-orally derived, transdermal IR-LED phototherapy could be prescribed with a high degree of patient compliance. However, IR-LED phototherapy was not found to affect the rate of OTM during the first three months of active extraction space closure in a split mouth design.PDF Image | Effect of LED Phototherapy on the Rate of Orthodontic Tooth Movement
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