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2 LITTERATURE REVIEW 2.3.2 Hormones related to circadian rhythm The circadian rhythm is connected to a line of hormones that regulate different processes in the human body according to variables as body tem- perature, sleep/wake, satiety, stress and event happiness (#Figure2+3). A short introduction to important regulators will follow. 2.3.2.1 Melatonin (sleep) Melatonin regulates the biological clock [section 2.3.1] that is controlled by the suprachiasmatic nucleus (SCN) turning different hormones on and off. The sleep-hormone Melatonin is produced by Corpus Pineale, closely con- nected to SCN producing higher levels in the dark hours of the day and low or non-detectable blood levels during daytime. (sundhed.dk, 2017) People with phase shift advance or delay can benefit from BLT [section 2.6.1] regulating the Melatonin segregation or as medication. Low levels of Melatonin occur in depression, but Mortola et al, found that Melatonin segregation rhythms are not differing from normal persons, to patients with AN and BN, without signs of depression. (Mortola, Laughlin and Yen, 1993) Fasting in healthy adults showed lover night-time Melatonin levels, but AN shows conflicting results. (Kennedy, 1994) Findings suggest no significance in the reduction of nocturnal Melatonin, so low weigh will not affect or disturb the Melatonin rhythm. In AN, not restrictive (with b/p) elevated Melatonin levels could suggest that it is regulated by the activity in neurotransmitters connected to this. Figure 3, mammalian hormone levels (Hickie, I. et al, 2013) Master thesis · MSc Lighting Design · Pernille Bech-Larsen · Fall 2017 19PDF Image | Healing with light
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