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Acta Ophthalmologica 2017 Fig. 4. Representative example of an eye categorized as AREDS 3 with mainly convex, homogenous and low reflective drusen larger than 125 lm. Baseline (Top) shows a drusen volume of 0.39 mm3 with a mean central 1-mm drusen with thickness of 29 lm. Black numbers indicate the mean drusen thickness of each early treatment diabetic retinopathy study subgrid and red numbers indicate the corresponding drusen volume (mm3). Bottom: Follow-up examination at visit 1. Overall drusen volume as well as mean central drusen thickness has significantly decreased without new formation of geographic atrophy or disruption of the photoreceptor layers. Fig. 5. An individual cut segmented subtraction scan showing significant drusen regression at 3 months following the treatment course. Best-corrected visual acuity in dry AMD may remain stable or slowly decline without rapid vision loss. Therefore, a small visual gain in this patient cohort is clinically relevant. In this case series, BCVA improved in over 90% of subjects with 59.5% achieving better than five letters and 11.9% achieving better than 10 letters on ETDRS BCVA testing, representing significant improvement in visual func- tion. Early treatment diabetic retinopa- thy study BCVA testing measurements with a logMAR score change of 0.1 (five letters) has been shown to be e275PDF Image | Photobiomodulation reduces drusen in macular degeneration
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