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Research Article iMedPub Journals www.imedpub.com DOI: 10.36648/2472-1905.6.3.59 Photodynamic Cosmetic Therapy on Melasma Management - Melan Reduxx Program Abstract The melasma has a multifactorial pathogenesis and a lot of strategies on treatment are proposed. However melasma has no a final treatment because depending of hormonal alteration, UV exposition frequently and other causes, the pigmentation comes again and in many cases stronger than before treatment. The aim of this study is to demonstrate that the management of melasma proposed in the melan reduxx program is possible by associating different treatment strategies as: professional procedures on clinical using low level light professional therapy with laser and LEDs, in different visible wavelengths in the presence of chemical and photoactived peels (professional cosmetics products) as well as home care procedures using topical and oral cosmetics products. The management of melasma can be realized from 3 to 4 months, decreasing the skin pigmentation gradually. The melan reduxx program is proposed to be performed from 5 to 15 sessions with intervals from fifteen to thirty days between sessions. In agreement with the results it is possible to perform the Photodynamic Cosmetic Therapy on melasma management on melan reduxx program using chemical and photoactived peels with safety and effectivity associating visible light and a lot of cosmetology. Keywords: Photodynamic cosmetic therapy; Melasma; Laser; Chemical peel; Photoactivated peel Received: July 11, 2020; Accepted: August 05, 2020; Published: August 12, 2020 Introduction 2020 Vol.6 No.3:10 Priscila Fernanda Campos Menezes1,2*, Nahdia Jackeline Souza Caixeta1 and Vanderlei Salvador Bagnato2 1 Belle la Pelle Clinica de Estética & Cursos Profissionalizantes – Araras-Sao Paulo, Brazil 2 Instituto de Física de São Carlos (IFSC) – University of São Paulo (USP), Av. Trabalhador São Carlense, Brazil *Corresponding author: Dr. Priscila Fernanda Campos Menezes priscilamene2015@gmail.com Tel: 551633739672 Instituto de Física de Sao Carlos (IFSC), University of Sao Paulo (USP), Av. Trabalhador Sao Carlense, 400 - CEP: 13560-970; Sao Carlos - Sao Paulo, Brazil. Citation: Menezes PFC, Caixeta NJS, Bagnato VS (2020) Photodynamic Cosmetic Therapy on Melasma Management - Melan Reduxx Program. J Aesthet Reconstr Surg Vol.6 No.3:10 One of the most frequently asked questions from patients to aesthetic health professionals is about the effective treatment of melasma. The answer to this question is "No," because melasma has no treatment but management. This means that melasma may be controlled, but at some point either by hormonal fluctuation, sun exposure and some kind of aggression in the skin that triggers an inflammatory reaction, it may come back more stronger with a lot of amount of melanin formed in the region (pigment rebound effect) [1-3]. Then we can say that the management of melasma can be defined as a treatment for all life. Melasma has a multifactorial pathogenesis that envolves the Genetic predisposition, hormonal factors, pregnancy, ultraviolet (UV) radiation exposure frequentely, farmaceutical drugs and cosmetics on skin, that play important role on increase in melanin deposition in the epidermis and dermis (epidermal and dermal melasma) [1,3-6]. During pregnancy, increased levels of estrogen and progesterone, that stimulates the alfa MSH receptor, increases the pigmentation on skin. The oral contraceptives also have been linked to skin hyperpigmentation since that increases the levels of estrogens stimulating the activity of melanocytes. On postmenopausal the levels of estrogen also increase by aromatase enzyme activity also stimulating the pigmentations on skin melasma. The patients with melasma shows in all stituation an increased expression of estrogen receptors at skin and many strategies has been done to act on selective estrogen receptor modulators – SERMs [7,8]. In this sense, some depigmenting active principles, even by different mechanisms, have as their final objective the decrease of spots and melasma on skin acting by different mechanisms as: promoting the degradation of superficial melanin on skin (peelings effect); inhibition of melanin production on skin by tyrosinase enzyme (melanogenese modulation); destruction of melanocytes by autophagy mechanisms; and also interfering on © Under License of Creative Commons Attribution 3.0 License | This article is available in: http://aesthetic-reconstructive-surgery.imedpub.com 1 Journal of Aesthetic & Reconstructive Surgery ISSN 2472-1905PDF Image | Photodynamic Cosmetic Therapy on Melasma Management
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