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Molecules 2020, 25, 4102 Molecules 2020, 25, x FOR PEER REVIEW Molecules 2020, 25, x FOR PEER REVIEW Molecules 2020, 25, x FOR PEER REVIEW 4 of 22 Photosensitiser Photosensitiser Photosensitiser Photosensitiser Hematoporphyrin Table 1. List of photosensitisers used in photodynamic therapy of various cancers. Table 1. List of photosensitisers used in photodynamic therapy of various cancers. Hemdaetroivpaotripvehsyrin Hematoporphyrin cLeruvnicga,lb, lbardedasetr,csaknicne,r. Lung, bladder, skin, [17,42] [17,42] derivatives cervical, breast cancer. derivatives 5-Aminolevulinic acid 5-Am5-iAnmoleinvoulleinvuiclianciicdacid 5-Aminolevulinic acid Second-Generation Photosensitisers cervical, breast cancer. Bladder, skin, lung, Bladdoevra,rsykain,dlung, Bladder, skin, lung, Commercial Name λ max (nm) Structure Table 1. List of photosensitisers used in photodynamic therapy of various cancers. Type of Cancer Reference [17,42] [43–45] Commercial Name λ max (nm) Type of Cancer Type of Cancer Reference Reference Reference Commercial Name Commercial Name PhottoffriinPhottoheme Photofrin Photoheme Photofrin Photoheme λ max (nm)First-Generation Photosensitiser λ max (nm) Type of Cancer Lung, bladder, skin, Table 1. List of photosensitisers used in photodynamic therapy of various cancers. 4 of 22 4 of 22 4 of 22 Hematoporphyrin derivatives 630 630 630 635 Lung, bladder, skin, cervical, bre[a1s7t,4ca2n] cer. Meta- tetra(hyMdreotxay-phenyl) Foscan 652 chlorin Molecules 2020, 25, x FOR PEER REVIEW Approved drug for Meta- thberotrnecahtimaleannt dof thAeptrperaotvmedendtroufg for the treatment of tetra(hycdhrloxriynphenyl) Foscan 652 Meta-tetra(theytrdar(ohxyydprhoexnyyplh)ecnhylol)rin Foscan 652 [46–48] oesobprohnacgheiallcaandcers. [46–48] [46–48] chlorin brronchiialland oesophageal cancers. oesophageal cancers. oesophageal cancers. Gynaecological Gdiysneaseecso,lopgroicsatal tdeiseases, prostate cancer, cafinbcreors,afirbcroomsar,cLoimvear, brain, lung[,4a9n–d51o]ral Liver, brain, lung, acanndcers. oral cancers. Prostate and skin [52,53] cancer. ChloCrhinloer6in e6 MACE MACEDACEEPhotoditazine Photoditazine 664 [49–51] Levulan LALeelvavusuellanansn [43–45] 635 Allassenss gastrcoaingctears.tirnoainltestinalcancer. Levulan Alasens 635 gastrointestinal [43–45] cancer. cancer. Approved drug for Apthperotrveeadtmderuntgoffor [46–48] 5 of 22 gasotvBroalarinydtdaeensrtd,insaklin, lung, ovary and ovary and [43–45] Benzoporphyrin Visudyne 690 Hepatocellular cancer,PDF Image | Role of Photoactive Phytocompounds in Photodynamic Therapy of Cancer
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