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Temozolomide Enhances Triple-Negative Breast Cancer Virotherapy

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Temozolomide Enhances Triple-Negative Breast Cancer Virotherapy ( temozolomide-enhances-triple-negative-breast-cancer-virother )

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Cancers 2018, 10, 144 14 of 15 10. Xia, Z.J.; Chang, J.H.; Zhang, L.; Jiang, W.Q.; Guan, Z.Z.; Liu, J.W.; Zhang, Y.; Hu, X.H.; Wu, G.H.; Wang, H.Q.; et al. Phase III randomized clinical trial of intratumoral injection of E1B gene-deleted adenovirus (H101) combined with cisplatin-based chemotherapy in treating squamous cell cancer of head and neck or esophagus. Ai Zheng 2004, 23, 1666–1670. [PubMed] 11. Heise, C.; Lemmon, M.; Kirn, D. Efficacy with a replication-selective adenovirus plus cisplatin-based chemotherapy: Dependence on sequencing but not p53 functional status or route of administration. Clin. Cancer Res. 2000, 6, 4908–4914. [PubMed] 12. Galanis, E.; Okuno, S.H.; Nascimento, A.G.; Lewis, B.D.; Lee, R.A.; Oliveira, A.M.; Sloan, J.A.; Atherton, P.; Edmonson, J.H.; Erlichman, C.; et al. Phase I-II trial of ONYX-015 in combination with map chemotherapy in patients with advanced sarcomas. Gene Ther. 2005, 12, 437–445. [CrossRef] [PubMed] 13. Koski, A.; Kangasniemi, L.; Escutenaire, S.; Pesonen, S.; Cerullo, V.; Diaconu, I.; Nokisalmi, P.; Raki, M.; Rajecki, M.; Guse, K.; et al. Treatment of cancer patients with a serotype 5/3 chimeric oncolytic adenovirus expressing gmcsf. Mol. Ther. 2010, 18, 1874–1884. [CrossRef] [PubMed] 14. Gozuacik, D.; Kimchi, A. Autophagy and cell death. Curr. Top. Dev. Biol. 2007, 78, 217–245. [PubMed] 15. Newman, R.A.; Kondo, Y.; Yokoyama, T.; Dixon, S.; Cartwright, C.; Chan, D.; Johansen, M.; Yang, P. Autophagic cell death of human pancreatic tumor cells mediated by oleandrin, a lipid-soluble cardiac glycoside. Integr. Cancer Ther. 2007, 6, 354–364. [CrossRef] [PubMed] 16. Rodriguez-Rocha, H.; Gomez-Gutierrez, J.G.; Garcia-Garcia, A.; Rao, X.M.; Chen, L.; McMasters, K.M.; Zhou, H.S. Adenoviruses induce autophagy to promote virus replication and oncolysis. Virology 2011, 416, 9–15. [CrossRef] [PubMed] 17. Friedman, H.S.; Kerby, T.; Calvert, H. Temozolomide and treatment of malignant glioma. Clin. Cancer Res. 2000, 6, 2585–2597. [PubMed] 18. Newlands, E.S.; Stevens, M.F.; Wedge, S.R.; Wheelhouse, R.T.; Brock, C. Temozolomide: A review of its discovery, chemical properties, pre-clinical development and clinical trials. Cancer Treat. Rev. 1997, 23, 35–61. [CrossRef] 19. O’Shaughnessy, J.A. Oral alkylating agents for breast cancer therapy. Drugs 1999, 58, 1–9. [CrossRef] [PubMed] 20. Trudeau, M.E.; Crump, M.; Charpentier, D.; Yelle, L.; Bordeleau, L.; Matthews, S.; Eisenhauer, E. Temozolomide in metastatic breast cancer (MBC): A phase II trial of the national cancer institute of Canada—Clinical trials group (NCIC-CTG). Ann. Oncol. 2006, 17, 952–956. [CrossRef] [PubMed] 21. Tatar, Z.; Thivat, E.; Planchat, E.; Gimbergues, P.; Gadea, E.; Abrial, C.; Durando, X. Temozolomide and unusual indications: Review of literature. Cancer Treat. Rev. 2013, 39, 125–135. [CrossRef] [PubMed] 22. Jiang, G.; Sun, C.; Li, R.H.; Wei, Z.P.; Zheng, J.N.; Liu, Y.Q. Enhanced antitumor efficacy of a novel oncolytic adenovirus combined with temozolomide in the treatment of melanoma in vivo. J. Cancer Res. Clin. Oncol. 2015, 141, 75–85. [CrossRef] [PubMed] 23. Kaliberova, L.N.; Krendelchtchikova, V.; Harmon, D.K.; Stockard, C.R.; Petersen, A.S.; Markert, J.M.; Gillespie, G.Y.; Grizzle, W.E.; Buchsbaum, D.J.; Kaliberov, S.A. CRADRGDflt-IL24 virotherapy in combination with chemotherapy of experimental glioma. Cancer Gene Ther. 2009, 16, 794–805. [CrossRef] [PubMed] 24. Tyler, M.A.; Ulasov, I.V.; Lesniak, M.S. Cancer cell death by design: Apoptosis, autophagy and glioma virotherapy. Autophagy 2009, 5, 856–857. [CrossRef] [PubMed] 25. Ulasov, I.V.; Tyler, M.A.; Zhu, Z.B.; Han, Y.; He, T.C.; Lesniak, M.S. Oncolytic adenoviral vectors which employ the survivin promoter induce glioma oncolysis via a process of beclin-dependent autophagy. Int. J. Oncol. 2009, 34, 729–742. [PubMed] 26. Gomez-Gutierrez, J.G.; Nitz, J.; Sharma, R.; Wechman, S.L.; Riedinger, E.; Martinez-Jaramillo, E.; Sam Zhou, H.; McMasters, K.M. Combined therapy of oncolytic adenovirus and temozolomide enhances lung cancer virotherapy in vitro and in vivo. Virology 2016, 487, 249–259. [CrossRef] [PubMed] 27. Garza-Morales, R.; Yaddanapudi, K.; Perez-Hernandez, R.; Riedinger, E.; McMasters, K.M.; Shirwan, H.; Yolcu, E.; Montes de Oca-Luna, R.; Gomez-Gutierrez, J.G. Temozolomide renders murine cancer cells susceptible to oncolytic adenovirus replication and oncolysis. Cancer Biol. Ther. 2018, 19, 188–197. [CrossRef] [PubMed] 28. Kabeya, Y.; Mizushima, N.; Ueno, T.; Yamamoto, A.; Kirisako, T.; Noda, T.; Kominami, E.; Ohsumi, Y.; Yoshimori, T. LC3, a mammalian homologue of yeast apg8p, is localized in autophagosome membranes after processing. EMBO J. 2000, 19, 5720–5728. [CrossRef] [PubMed]

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