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Group Day 1 Day 3 Day 7 Day 12 Day 17 Figure 3: Percent of original wound area in Control 100 73.5 ± 7.9 41.4 ± 8.4 20.4 ± 3.8 12.4 ± 2.9 LED only 100 69.2± 5.7 33.2± 6.2 14.1± 3.7 8.1± 2.0 Figure 4: Type II Diabetic Mice with excisional skin wounds treated with 3 LED wavelengths, 50 mW/cm2, 4 J/cm2. The square root of wound area is used in the dependent variable in the analysis. This transformation was needed to correct for non-constant error in the General Linear Model. SqrtArea could be in- terpreted as being proportional to the radius of a circular wound. experimental controls and LED treated rats. 1.2 1 0.8 0.6 0.4 0.2 0 Control LED MEAN (Wound_Area cm2) MEAN (SqrtArea) 180 160 140 120 100 80 60 40 20 0 24 hr 48hr control 670nm 728nm 880nm Figure 6. 3T3 Fibroblast DNA synthesis 3- hour incubation; LED 50 mW/cm2; 4, 8, 12 J/cm2. 36 Figure 5. 3T3 Fibroblast DNA Synthesis 8 J/cm2, 50 mW/cm2, individual wavelengths. 24- and 48- hour 3H thymidine incor- poration. 600 500 400 300 200 100 0 3 Hours Incubation After LED 1 Control 4J 8J 12J % Change From Control % Change From ControlPDF Image | THE USE OF NASA LED NEAR-INFRARED TECHNOLOGY FOR BIOSTIMULATION
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