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Healthcare 2020, 8, 10 6 of 14 Characteristic Healthcare 2020, 8, x FOR PEER REVAIgEeWin years, mean (SD) Female Mean (SD) or n (Percentage) 54.2 (17.7) 7 (78%) 6 of 14 Table 1. Baseline patient characteristics (N = 9). Chemotherapy 4 (44%) Hispanic 3 (33%) Radiation 3 (33%) 4 (44%) Hormonal Depressed (PHQ8 ≥ 10) 6 (67%) PHQ-8 score, mean (SD) 9.7 (2.2) Prescribed antidepressants Receiving psychotherapy 4 (44%) Race: White Black 7 (78%) 1 (11%) Other 1 (11%) Cancer type: Current depression treatment: 5 (56%) 2 (227%)(78%) Breast Receiving any depTrheysrosidon treatment Bone 1 (11%) Skin 1 (11%) Prior cancer treatment: 6 (67%) 3 (33%) Complementary and alternative medicine Surgery Decision-mCahkeimngothperreafpeyrence: 7 (78%) Radiation 3 (33%) I want doctor to decide 0 (0%) Hormonal 4 (44%) I want doctor to consider my ideas CIurwreannt dtetporedsesicoindtereatment: Receiving any depression treatment 1 (11%) Depressed (PHQ8 ≥ 10) I want doctor anPdHIQt-o8 mscoarke,emdeeanci(sSiDo)ns together 6 (67%) 9.7 (26.2)(67%) 4 (44%) PHQ-8—patient health questionnaire; SD—standard deviation. Prescribed antidepressants Receiving psychotherapy 3.1. Outcomes and EstCimomatpiloenmentary and alternative medicine I want doctor to decide 0 (0%) Decision-making preference: The results of the individual personalized trials are presented in Table 2 and in Figure A2. 7 (78%) 4 (44%) 6 (67%) 3 (33%) 2 (22%) Overall, BWL was associated with significantly fewer patient-reported depressive symptoms in two I want doctor to consider my ideas 1 (11%) patients, no signifiIcwanantt doifcfteor eandceI tionmfaikvedpecaistioensttso,gaetnhder worse depr6e(s6s7i%v)e symptoms in one patient I want to decide 2 (22%) (Figure 2). A similar pattern was observed with respect to fatigue symptoms, with just one patient PHQ-8—patient health questionnaire; SD—standard deviation. reporting lower fatigue, six patients reporting no difference in fatigue severity, and one patient reporting higher fatigue with BWL versus DRL. Figure 2. Within-patient differences in depressive symptoms using bright white light therapy (BWL) Figure 2. Within-patient differences in depressive symptoms using bright white light therapy (BWL) versus dim red light therapy (DRL). Depressive symptoms were modeled adjusting for linear time versus dim red light therapy (DRL). Depressive symptoms were modeled adjusting for linear time trendtraend ancdcoaucncotiunngtinfogrfoaruatouctocrorrerlealtaitoionnssoone day aparrt,t,pp<<0.05.05dedneonteodtesdtatsistatitciasltisciaglnisfigcannicfiec.ance. WhiteWdhiiatemdoinamdoindicnadtiecsatseisgsnigifincifaicnatnlytlylolwoweerrdeepressivesympptotomms ws withitBhWBLW, rLe,drdediamdioanmdoindiciantdesicates significantly higher depressive symptoms with BWL, and blue diamond indicates no significant significantly higher depressive symptoms with BWL, and blue diamond indicates no significant difference in depressive symptoms between BWL and DRL. difference in depressive symptoms between BWL and DRL.PDF Image | Bright White Light Therapy for Depression in Cancer Survivors
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