Photobiomodulation with 670 nm light ameliorates retinal

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Photobiomodulation with 670 nm light ameliorates retinal ( photobiomodulation-with-670-nm-light-ameliorates-retinal )

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ACCEPTED MANUSCRIPT inflammation during retinal stress. As a non-invasive and relatively non-expensive treatment, 670nm light has adjuvant therapeutic potential for retinal degenerations where inflammation, macrophage recruitment and photoreceptor loss play a key role. Acknowledgments This work was supported by the Australian Government National Health and Medical Research Council Grant (APP1049990), the Australian Government Research Training Program and the Gretel and Gordon Bootes Foundation. Conflict of interest The authors declare that they have no conflicts of interest with the contents of this article. Authors’ contributions YZL designed the experiments, conducted the experiments as well as analysis, and wrote the paper; RN conceived the study, designed the experiments, and revised paper; MM conceived the study, designed the experiments, and revised paper; NF edited and revised the paper; KS conducted the experiments and acquired data; RAB supported techniques. HJ supported techniques; JP conceived the study and interpreted data; KV obtained funding, conceived the study, designed the experiments, and revised paper; all contributing authors have read and approved the final version of the paper. References Abrahan, C.E., Insua, M.F., Politi, L.E., German, O.L., Rotstein, N.P., 2009. Oxidative stress promotes proliferation and dedifferentiation of retina glial cells in vitro. Journal of neuroscience research 87, 964-977. Albarracin, R., Eells, J., Valter, K., 2011. Photobiomodulation protects the retina from light-induced photoreceptor degeneration. Investigative ophthalmology & visual science 52, 3582-3592. Albarracin, R., Natoli, R., Rutar, M., Valter, K., Provis, J., 2013. 670 nm light mitigates oxygen- induced degeneration in C57BL/6J mouse retina. BMC neuroscience 14, 125. 21 ACCEPTED MANUSCRIPT

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