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ACCEPTED MANUSCRIPT Albarracin, R., Valter, K., 2012. 670 nm red light preconditioning supports Muller cell function: evidence from the white light-induced damage model in the rat retina. Photochemistry and photobiology 88, 1418-1427. Ambati, J., Atkinson, J.P., Gelfand, B.D., 2013. Immunology of age-related macular degeneration. Nature reviews. Immunology 13, 438-451. Begum, R., Powner, M.B., Hudson, N., Hogg, C., Jeffery, G., 2013. Treatment with 670 nm light up regulates cytochrome C oxidase expression and reduces inflammation in an age-related macular degeneration model. PloS one 8, e57828. Bringmann, A., Iandiev, I., Pannicke, T., Wurm, A., Hollborn, M., Wiedemann, P., Osborne, N.N., Reichenbach, A., 2009. Cellular signaling and factors involved in Muller cell gliosis: neuroprotective and detrimental effects. Progress in retinal and eye research 28, 423-451. Bringmann, A., Pannicke, T., Grosche, J., Francke, M., Wiedemann, P., Skatchkov, S.N., Osborne, N.N., Reichenbach, A., 2006. Muller cells in the healthy and diseased retina. Progress in retinal and eye research 25, 397-424. Bringmann, A., Wiedemann, P., 2012. Muller glial cells in retinal disease. Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 227, 1-19. Brosseau, L., Robinson, V., Wells, G., Debie, R., Gam, A., Harman, K., Morin, M., Shea, B., Tugwell, P., 2005. Low level laser therapy (Classes I, II and III) for treating rheumatoid arthritis. The Cochrane database of systematic reviews, CD002049. Calaza, K.C., Kam, J.H., Hogg, C., Jeffery, G., 2015. Mitochondrial decline precedes phenotype development in the complement factor H mouse model of retinal degeneration but can be corrected by near infrared light. Neurobiology of aging 36, 2869-2876. Chen, M., Xu, H., 2012. Inflammation in Age-Related Macular Degeneration – Implications for Therapy, Inflammatory Diseases Immunopathology, Clinical and Pharmacological Bases, Dr Mahin Khatami (Ed.). Cornish, E.E., Madigan, M.C., Natoli, R., Hales, A., Hendrickson, A.E., Provis, J.M., 2005. Gradients of cone differentiation and FGF expression during development of the foveal depression in macaque retina. Visual neuroscience 22, 447-459. Desmet, K.D., Paz, D.A., Corry, J.J., Eells, J.T., Wong-Riley, M.T., Henry, M.M., Buchmann, E.V., Connelly, M.P., Dovi, J.V., Liang, H.L., Henshel, D.S., Yeager, R.L., Millsap, D.S., Lim, J., Gould, L.J., Das, R., Jett, M., Hodgson, B.D., Margolis, D., Whelan, H.T., 2006. Clinical and experimental applications of NIR-LED photobiomodulation. Photomedicine and laser surgery 24, 121-128. Diaz, F., 2010. Cytochrome c oxidase deficiency: patients and animal models. Biochimica et biophysica acta 1802, 100-110. Doyle, S.L., Campbell, M., Ozaki, E., Salomon, R.G., Mori, A., Kenna, P.F., Farrar, G.J., Kiang, A.- S., Humphries, M.M., Lavelle, E.C., O'Neill, L.A.J., Hollyfield, J.G., Humphries, P., 2012a. NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components. Nature medicine 18, 791-798. Doyle, S.L., Campbell, M., Ozaki, E., Salomon, R.G., Mori, A., Kenna, P.F., Farrar, G.J., Kiang, A.S., Humphries, M.M., Lavelle, E.C., O'Neill, L.A., Hollyfield, J.G., Humphries, P., 2012b. NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components. Nature medicine 18, 791-798. Fernando, N., Natoli, R., Valter, K., Provis, J., Rutar, M., 2016. The broad-spectrum chemokine inhibitor NR58-3.14.3 modulates macrophage-mediated inflammation in the diseased retina. Journal of neuroinflammation 13, 47. Gavish, L., Asher, Y., Becker, Y., Kleinman, Y., 2004. Low level laser irradiation stimulates mitochondrial membrane potential and disperses subnuclear promyelocytic leukemia protein. Lasers in surgery and medicine 35, 369-376. Geneva, II, 2016. Photobiomodulation for the treatment of retinal diseases: a review. International journal of ophthalmology 9, 145-152. Giacci, M.K., Wheeler, L., Lovett, S., Dishington, E., Majda, B., Bartlett, C.A., Thornton, E., Harford-Wright, E., Leonard, A., Vink, R., Harvey, A.R., Provis, J., Dunlop, S.A., Hart, N.S., Hodgetts, S., Natoli, R., Van Den Heuvel, C., Fitzgerald, M., 2014. Differential effects of 670 and 830 22 ACCEPTED MANUSCRIPTPDF Image | Photobiomodulation with 670 nm light ameliorates retinal
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