PDF Publication Title:
Text from PDF Page: 082
CHAPTER 3 sensitivity scores in light treated animals (Figure 3.2) could not have resulted from locomotor deficits. Figure 3.4 Locomotor recovery is improved by red light treatment following T10 hemicontusion spinal cord injury. Daily locomotor scores (BBB, see methods) following a right-sided hemicontusion spinal cord injury are shown for the contralateral (a) and ipsilateral (b) sides. Red light treatment results in significant locomotor improvements on both sides over the period indicated by the black bar (large asterisk, ANOVA/linear mixed effects model with repeated measures). Point-wise comparisons between groups for individual time points are also shown (small asterisks, Student’s t-test). Individual data points are presented as open square or circular dots; lines indicate the group means. * p < 0.05; ** p < 0.01. 3.4.6 Red light reduces cell death at the injury zone To examine the effect of red light on cell death following injury, the number of TUNEL+ cells was quantified at 1, 3 and 7 days post-injury in dorsal regions of the T10 spinal cord (Figure 3.5, n = 5 for each time point). The SCI group resulted in an increased density of TUNEL+ cells in the dorsal spinal cord ipsilateral to the injury as early as day 1 (contralateral 1.5 ± 1.5 cells/mm2; ipsilateral 96.8 ± 41.1 cells/mm2), reaching maximum levels by day 3 (contralateral 13.1 ± 5.6 cells/mm2; ipsilateral 126.8 ± 41.5 cells/mm2). The contralateral side had much fewer cells where maximum levels were reached by day 7 (Figure 3.5; contralateral 32.5 ± 32.5 cells/mm2; ipsilateral 74.2 ± 43.7 cells/mm2). Red light treatment resulted in a significant group reduction of TUNEL+ cells in the ipsilateral side, notably significant at the day 3 time point when TUNEL+ cells were maximal in the sham-treated group (1-dpi: 49.6 ± 25.2 cells/mm2; 3-dpi 18.2 ± 3.9 cells/mm2; 7-dpi 22.0 ± 6.1 cells/mm2). There was no significant difference in TUNEL labelling 68PDF Image | Effects of Red Light Treatment on Spinal Cord Injury
PDF Search Title:
Effects of Red Light Treatment on Spinal Cord InjuryOriginal File Name Searched:
Thesis_Di Hu_final.pdfDIY PDF Search: Google It | Yahoo | Bing
Cruise Ship Reviews | Luxury Resort | Jet | Yacht | and Travel Tech More Info
Cruising Review Topics and Articles More Info
Software based on Filemaker for the travel industry More Info
The Burgenstock Resort: Reviews on CruisingReview website... More Info
Resort Reviews: World Class resorts... More Info
The Riffelalp Resort: Reviews on CruisingReview website... More Info
CONTACT TEL: 608-238-6001 Email: greg@cruisingreview.com (Standard Web Page)