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Red Light Therapy at 660nm Improves Eyesight

Red Light Improves Eyesight

Recent studies (June 2020) confirm that for adults over 40, a red spectrum (LLLT or Low level light therapy) light can help the functioning of mitochondria.

There was a 14 percent improvement in the ability to see colors, or cone color contrast sensitivity, for the entire two dozen participants.

The spectrum for this therapeutic red light is around 660 nm. I have been using the Amzcool device (shown to the left and link below) for almost a year now, and love it. I use it for both my eyes, and for knee pain. It works for both eyes and skin healing (verfied by NASA).

For more details, please follow the link for our detailed review.

Science and Literature for Red Light Therapy

For More Info…

Buy Now: Amzcool Red Light Therapy Disc on Amazon (3.4 inch disc)

Email: Red Light Therapy Questions

Red Light Therapy Science Links
Amzcool red light device tested 670 nm red light spectrum

Experience with Red Light Therapy

How did I find out about this ? I purchased an LED light for a indoor hydroponics garden from Amazon, and over the span of a few days, noticed my eyesight improving. I used the Red LED setting. I couldn't believe it. So I started researching it, and sure enough, a recent study just confirmed what I actually experienced. I'm living proof that it indeed works.

More recently I have purchased the Amzcool red light device, which is specifically for the 670 nm red spectrum for the studies shown.

I had my electrical engineer friend do a spectrum analyzing test for the device and it was indeed 670 nm (as claimed).

Amazon Amzcool Red Light Therapy Disc (purchase link)

Amazon: Buy Now Red Light Therapy Device




Amzcool red light device tested 670 nm red light spectrum
The 670 nam spectrum matches what was indicated in the scientific studies. Analysis updated on August 13, 2020
Red Light Therapy at 660nm Improves Eyesight

Red Light Therapy I use Every Day

I use this Amzcool unit every day, and it is rechargeable and great for travel use. The unit is charged via USB and can be used for both eyes and skin applications as indicated by NASA studies (see references below). It is no longer available on Amazon.

Science and Literature for Red Light Therapy

Red Light Therapy at 660nm Improves Eyesight

Pilots

If you're like me (and over 40), you're concerned about your day and night vision getting worse, and your glasses prescription getting stronger. Help your vision using this simple technique. It works. I'm a Commercial, B727 Flight Engineer, Instrument Rated pilot. So whether your a weekend warrior, fly commercial for a living, or a military pilot, do the research and try for yourself. This is the easiest way to better your eyesight.

Science and Literature for Red Light Therapy

Buy Now: Amzcool Red Light Therapy Disc on Amazon (3.4 inch disc)

Email: Red Light Therapy Questions

Red Light Therapy Science Links

Red Light Therapy at 660nm Improves Eyesight Inside the Device
Red Light Therapy at 660nm Improves Eyesight Inside the Device
Red Light Therapy at 660nm

References From NIH and other Scientific Sources:

Declining eyesight improved by looking at deep red light. Researchers found the 670nm light had no impact in younger individuals, but in those around 40 years and over, significant improvements were obtained. Cone colour contrast sensitivity (the ability to detect colours) improved by up to 20 percent in some people aged around 40 and over. Improvements were more significant in the blue part of the colour spectrum that is more vulnerable in ageing. Rod sensitivity (the ability to see in low light) also improved significantly in those aged around 40 and over, though less than colour contrast.

Declining eyesight improved by looking at deep red light (science link)

Red Light Therapy at 660nm

Declining eyesight can be improved by looking at red light, pilot study says

A few minutes of looking into a deep red light could have a dramatic effect on preventing eyesight decline as we age, according to a new study published this week in The Journals of Gerontology. You don't need to use it for very long to start getting a strong result, said lead author Glen Jeffery, a professor of neuroscience at University College London's Institute of Ophthalmology.  

Declining eyesight can be improved by looking at red light, pilot study says (science link)

Red Light Therapy at 660nm improves eyesight

Can Looking at Deep Red Light Improve Declining Eyesight ?

Staring at a deep red light for 3 minutes a day can significantly improve declining eyesight in people aged over 40 years, finds a new UK study, which is the first of its kind in humans. Scientists believe the discovery, published in the Journals of Gerontology , could signal the dawn of new affordable home-based eye therapies to help people with naturally declining vision. At around 40 years, human retinal cell ageing accelerates, leading to vision deterioration.

Can Looking at Deep Red Light Improve Declining Eyesight ? (science link)

Red Light Therapy at 660nm improves eyesight

Photobiomodulation for the treatment of retinal diseases

Photobiomodulation (PBM), also known as low level laser therapy, has recently risen to the attention of the ophthalmology community as a promising new approach to treat a variety of retinal conditions including age-related macular degeneration, retinopathy of prematurity, diabetic retinopathy, Leber's hereditary optic neuropathy, amblyopia, methanol-induced retinal damage, and possibly others.

This review evaluates the existing research pertaining to PBM applications in the retina, with a focus on the mechanisms of action and clinical outcomes.

All available literature until April 2015 was reviewed using PubMed and the following keywords: photobiomodulation AND retina, low level light therapy AND retina, low level laser therapy AND retina, and FR/NIR therapy AND retina.

In addition, the relevant references listed within the papers identified through PubMed were incorporated. The literature supports the conclusion that the low-cost and non-invasive nature of PBM, coupled with the first promising clinical reports and the numerous preclinical-studies in animal models, make PBM well-poised to become an important player in the treatment of a wide range of retinal disorders.

Nevertheless, large-scale clinical trials will be necessary to establish the PBM therapeutic ranges for the various retinal diseases, as well as to gain a deeper understanding of its mechanisms of action. 

Keywords: photobiomodulation, low level laser therapy, age related macular degeneration, retinopathy of prematurity, far red to near-infrared, retinal degeneration, amblyopia, retinitis pigmentosa, methanol toxicity

Photobiomodulation for the treatment of retinal diseases (science link)

Red Light Therapy at 660nm improves eyesight

Aging retinal function is improved by near infrared light (670 nm) that is associated with corrected mitochondrial decline

Aging is associated with cellular decline and reduced function, partly mediated by mitochondrial compromise. However, aged mitochondrial function is corrected with near infrared light (670 nm) that improves their membrane potentials and adenosine triphosphate production and also reduces age-related inflammation. We ask if 670 nm light can also improve declining retinal function.

Electroretinograms were measured in 2-, 7-, and 12-month old C57BL/6 mice. Significant age-related declines were measured in the photoreceptor generated a-wave and the postreceptoral b-wave. Seven- and 12-month-old mice were exposed to 670 nm for 15 minutes daily over 1 month.

These showed significant improved retinal function in both waves of approximately 25 percent but did not reach levels found in 2-month-old animals. Our data suggest, 670 nm light can significantly improve aged retinal function, perhaps by providing additional adenosine triphosphate production for photoreceptor ion pumps or reduced aged inflammation. This may have implications for the treatment of retinal aging and age-related retinal disease, such as macular degeneration. 

Aging retinal function is improved by near infrared light (670 nm) that is associated with corrected mitochondrial decline (science link)

Red Light Therapy at 660nm improves eyesight

Light Therapy: Is It Safe for the Eyes?

Objective: Light therapy has become an increasingly popular treatment for depression and a range of other neuropsychiatric conditions. Yet, concerns have been raised about the ocular safety of light therapy. Method: We conducted the first systematic review into the ocular safety of light therapy. A PubMed search on January 4, 2017, identified 6708 articles, of which 161 were full-text reviewed. In total, 43 articles reporting on ocular complaints and ocular examinations were included in the analyses. Results: Ocular complaints, including ocular discomfort and vision problems, were reported in about 0% to 45% of the participants of studies involving light therapy. Based on individual studies, no evident relationship between the occurrence of complaints and light therapy dose was found. There was no evidence for ocular damage due to light therapy, with the exception of one case report that documented the development of a maculopathy in a person treated with the photosensitizing antidepressant clomipramine. Conclusion: Results suggest that light therapy is safe for the eyes in physically healthy, unmedicated persons. The ocular safety of light therapy in persons with preexisting ocular abnormalities or increased photosensitivity warrants further study. However, theoretical considerations do not substantiate stringent ocular safety-related contraindications for light therapy.

Light Therapy: Is It Safe for the Eyes? (science link)

Red Light Therapy at 660nm improves eyesight

Low-Intensity Far-Red Light Inhibits Early Lesions That Contribute to Diabetic Retinopathy: In Vivo and In Vitro

Purpose. Treatment with light in the far-red to near-infrared region of the spectrum (photobiomodulation [PBM]) has beneficial effects in tissue injury. We investigated the therapeutic efficacy of 670-nm PBM in rodent and cultured cell models of diabetic retinopathy. Methods. Studies were conducted in streptozotocin-induced diabetic rats and in cultured retinal cells. Diabetes-induced retinal abnormalities were assessed functionally, biochemically, and histologically in vivo and in vitro. 

Results. We observed beneficial effects of PBM on the neural and vascular elements of retina. Daily 670-nm PBM treatment (6 J/cm2) resulted in significant inhibition in the diabetes-induced death of retinal ganglion cells, as well as a 50 percent improvement of the ERG amplitude (photopic b wave responses) (both 0.01). To explore the mechanism for these beneficial effects, we examined physiologic and molecular changes related to cell survival, oxidative stress, and inflammation. PBM did not alter cytochrome oxidase activity in the retina or in cultured retinal cells. PBM inhibited diabetes-induced superoxide production and preserved MnSOD expression in vivo. Diabetes significantly increased both leukostasis and expression of ICAM-1, and PBM essentially prevented both of these abnormalities. In cultured retinal cells, 30-mM glucose exposure increased superoxide production, inflammatory biomarker expression, and cell death. PBM inhibited all of these abnormalities. Conclusions. PBM ameliorated lesions of diabetic retinopathy in vivo and reduced oxidative stress and cell death in vitro. PBM has been documented to have minimal risk. PBM is noninvasive, inexpensive, and easy to administer.

We conclude that PBM is a simple adjunct therapy to attenuate the development of diabetic retinopathy.

Low-Intensity Far-Red Light Inhibits Early Lesions That Contribute to Diabetic Retinopathy: In Vivo and In Vitro (science link)

Red Light Therapy at 660nm improves eyesight

Wound Healing | Adjunctive 830 nm light-emitting diode therapy can improve the results following aesthetic procedures

Background: Aggressive, or even minimally aggressive, aesthetic interventions are almost inevitably followed by such events as discomfort, erythema, edema and hematoma formation which could lengthen patient downtime and represent a major problem to the surgeon. Recently, low level light therapy with light-emitting diodes (LED-LLLT) at 830 nm has attracted attention in wound healing indications for its anti-inflammatory effects and control of erythema, edema and bruising. 

Rationale: The wavelength of 830 nm offers deep penetration into living biological tissue, including bone. A new-generation of 830 nm LEDs, based on those developed in the NASA Space Medicine Laboratory, has enabled the construction of planar array-based LED-LLLT systems with clinically useful irradiances. Irradiation with 830 nm energy has been shown in vitro and in vivo to increase the action potential of epidermal and dermal cells significantly. The response of the inflammatory stage cells is enhanced both in terms of function and trophic factor release, and fibroblasts demonstrate superior collagenesis and elastinogenesis. 

Conclusions: A growing body of clinical evidence is showing that applying 830 nm LED-LLLT as soon as possible post-procedure, both invasive and noninvasive, successfully hastens the resolution of sequelae associated with patient downtime in addition to significantly speeding up frank wound healing. This article reviews that evidence, and attempts to show that 830 nm LED-LLLT delivers swift resolution of postoperative sequelae, minimizes downtime and enhances patient satisfaction. 

Wound Healing: Adjunctive 830 nm light-emitting diode therapy can improve the results following aesthetic procedures (science link)

Research progress about the effect and prevention of blue light on eyes

In recent years, people have become increasingly attentive to light pollution influences on their eyes. In the visible spectrum, short-wave blue light with wavelength between 415 nm and 455 nm is closely related to eye light damage. This high energy blue light passes through the cornea and lens to the retina causing diseases such as dry eye, cataract, age-related macular degeneration, even stimulating the brain, inhibiting melatonin secretion, and enhancing adrenocortical hormone production, which will destroy the hormonal balance and directly affect sleep quality. Therefore, the effect of Blu-rays on ocular is becoming an important concern for the future. We describe blue light's effects on eye tissues, summarize the research on eye injury and its physical prevention and medical treatment. 

Research progress about the effect and prevention of blue light on eyes (science link)

Research progress about the effect and prevention of blue light on eyes (science link)

Low-level light therapy of the eye and brain

Low-level light therapy (LLLT) using red to near-infrared light energy has gained attention in recent years as a new scientific approach with therapeutic applications in ophthalmology, neurology, and psychiatry. The ongoing therapeutic revolution spearheaded by LLLT is largely propelled by progress in the basic science fields of photobiology and bioenergetics.

This paper describes the mechanisms of action of LLLT at the molecular, cellular, and nervous tissue levels. Photoneuromodulation of cytochrome oxidase activity is the most important primary mechanism of action of LLLT. Cytochrome oxidase is the primary photoacceptor of light in the red to near-infrared region of the electromagnetic spectrum. It is also a key mitochondrial enzyme for cellular bioenergetics, especially for nerve cells in the retina and the brain.

Evidence shows that LLLT can secondarily enhance neural metabolism by regulating mitochondrial function, intraneuronal signaling systems, and redox states. Current knowledge about LLLT dosimetry relevant for its hormetic effects on nervous tissue, including noninvasive in vivo retinal and transcranial effects, is also presented. Recent research is reviewed that supports LLLT potential benefits in retinal disease, stroke, neurotrauma, neurodegeneration, and memory and mood disorders. Since mitochondrial dysfunction plays a key role in neurodegeneration, LLLT has potential significant applications against retinal and brain damage by counteracting the consequences of mitochondrial failure. Upon transcranial delivery in vivo, LLLT induces brain metabolic and antioxidant beneficial effects, as measured by increases in cytochrome oxidase and superoxide dismutase activities. Increases in cerebral blood flow and cognitive functions induced by LLLT have also been observed in humans.

Importantly, LLLT given at energy densities that exert beneficial effects does not induce adverse effects. This highlights the value of LLLT as a novel paradigm to treat visual, neurological, and psychological conditions, and supports that neuronal energy metabolism could constitute a major target for neurotherapeutics of the eye and brain.

Low-level light therapy of the eye and brain (science link)

Low-level light therapy of the eye and brain (science link)

Effect of 670-nm Light-Emitting Diode Light On Neuronal Cultures

Light close to and within the near infrared range has documented benefits for promoting wound healing in human and animal studies. Our preliminary results using light-emitting diodes (LEDs) in this range have also demonstrated two-to five-fold increases in growth-phase-specific DNA synthesis in normal fibroblasts, muscle cells, osteoblasts, and mucosal epithelial cells in tissue cultures. However, the mechanisms of action of such light on cells are poorly understood. We hypothesized that the therapeutic effects of such light result from the stimulation of cellular events associated with increases in cytochrome oxidase activity. As a first step in testing our hypothesis, we subjected primary neuronal cultures to impulse blockade by tetrodotoxin (TTX), a voltage-dependent sodium channel blocker, and applied LED light at 670 nm to determine if it could partially or fully reverse the reduction of cytochrome oxidase activity by TTX. The wavelength and parameters were previously tested to be beneficial for wound healing.

Effect of 670-nm Light-Emitting Diode Light On Neuronal Cultures (science link)

Effect of 670-nm Light-Emitting Diode Light On Neuronal Cultures (science link)

LLLT using Light Emitting Diodes research list

Yet another NASA NIR LED therapy paper was published recently showing that LED treatment may be therapeutic to damaged neurons, this time in a Parkinson’s disease model.

LLLT using Light Emitting Diodes research list (science link)

LLLT using Light Emitting Diodes research list (science link)

Effect of 660 nm Light-Emitting Diode on the Wound Healing in Fibroblast-Like Cell Lines

Abstract: Light in the red to near-infrared (NIR) range (630–1000 nm), which is generated using low energy laser or light-emitting diode (LED) arrays, was reported to have a range of beneficial biological effects in many injury models. NIR via a LED is a well-accepted therapeutic tool for the treatment of infected, ischemic, and hypoxic wounds as well as other soft tissue injuries in humans and animals. This study examined the effects of exposure to 660 nm red LED light at intensities of 2.5, 5.5, and 8.5 mW/cm2 for 5, 10, and 20 min on wound healing and proliferation in fibroblast-like cells, such as L929 mouse fibroblasts and human gingival fibroblasts (HGF-1). A photo illumination-cell culture system was designed to evaluate the cell proliferation and wound healing of fibroblast-like cells exposed to 600 nm LED light. The cell proliferation was evaluated by MTT assay, and a scratched wound assay was performed to assess the rate of migrating cells and the healing effect. Exposure to the 660 nm red LED resulted in an increase in cell proliferation and migration compared to the control, indicating its potential use as a phototherapeutic agent.

Effect of 660 nm Light-Emitting Diode on the Wound Healing in Fibroblast-Like Cell Lines (science link)

Effect of 660 nm Light-Emitting Diode on the Wound Healing in Fibroblast-Like Cell Lines (science link)

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